| Reaction Details |
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 | Report a problem with these data |
| Target | Bradykinin B1 receptor |
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| Ligand | BDBM50420594 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_841721 |
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| Ki | 12±n/a nM |
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| Citation |  Barth, M; Bondoux, M; Luccarini, JM; Peyrou, V; Dodey, P; Pruneau, D; Massardier, C; Paquet, JL From bradykinin B2 receptor antagonists to orally active and selective bradykinin B1 receptor antagonists. J Med Chem55:2574-84 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Bradykinin B1 receptor |
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| Name: | Bradykinin B1 receptor |
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| Synonyms: | B1 BRADYKININ | B1 bradykinin receptor | B1R | BK-1 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 40508.87 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P46663 |
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| Residue: | 353 |
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| Sequence: | MASSWPPLELQSSNQSQLFPQNATACDNAPEAWDLLHRVLPTFIISICFFGLLGNLFVLL
VFLLPRRQLNVAEIYLANLAASDLVFVLGLPFWAENIWNQFNWPFGALLCRVINGVIKAN
LFISIFLVVAISQDRYRVLVHPMASRRQQRRRQARVTCVLIWVVGGLLSIPTFLLRSIQA
VPDLNITACILLLPHEAWHFARIVELNILGFLLPLAAIVFFNYHILASLRTREEVSRTRC
GGRKDSKTTALILTLVVAFLVCWAPYHFFAFLEFLFQVQAVRGCFWEDFIDLGLQLANFF
AFTNSSLNPVIYVFVGRLFRTKVWELYKQCTPKSLAPISSSHRKEIFQLFWRN
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| BDBM50420594 |
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| Name | BDBM50420594 |
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| Synonyms: | CHEMBL2087036 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H26Cl2N4O3S |
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| Mol. Mass. | 509.449 |
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| SMILES | CN(Cc1ccc(cc1)C1=NCCN1)C(=O)\C=C\CN(C)S(=O)(=O)c1ccc(Cl)c(C)c1Cl |t:10| |
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| Structure | 
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| n/a |
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