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TargetBradykinin B1 receptor
LigandBDBM50420594
Substrate/Competitorn/a
Meas. Tech.ChEMBL_841721
Ki 12±n/a nM
Citation Barth, MBondoux, MLuccarini, JMPeyrou, VDodey, PPruneau, DMassardier, CPaquet, JL From bradykinin B2 receptor antagonists to orally active and selective bradykinin B1 receptor antagonists. J Med Chem55:2574-84 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Bradykinin B1 receptor
Name:Bradykinin B1 receptor
Synonyms:B1 BRADYKININ | B1 bradykinin receptor | B1R | BK-1 receptor
Type:Enzyme
Mol. Mass.:40508.87
Organism:Homo sapiens (Human)
Description:P46663
Residue:353
Sequence:
MASSWPPLELQSSNQSQLFPQNATACDNAPEAWDLLHRVLPTFIISICFFGLLGNLFVLL
VFLLPRRQLNVAEIYLANLAASDLVFVLGLPFWAENIWNQFNWPFGALLCRVINGVIKAN
LFISIFLVVAISQDRYRVLVHPMASRRQQRRRQARVTCVLIWVVGGLLSIPTFLLRSIQA
VPDLNITACILLLPHEAWHFARIVELNILGFLLPLAAIVFFNYHILASLRTREEVSRTRC
GGRKDSKTTALILTLVVAFLVCWAPYHFFAFLEFLFQVQAVRGCFWEDFIDLGLQLANFF
AFTNSSLNPVIYVFVGRLFRTKVWELYKQCTPKSLAPISSSHRKEIFQLFWRN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50420594
NameBDBM50420594
Synonyms:CHEMBL2087036
TypeSmall organic molecule
Emp. Form.C23H26Cl2N4O3S
Mol. Mass.509.449
SMILESCN(Cc1ccc(cc1)C1=NCCN1)C(=O)\C=C\CN(C)S(=O)(=O)c1ccc(Cl)c(C)c1Cl |t:10|
Structure
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