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Target
P2Y purinoceptor 6
Ligand
BDBM50403871
Substrate
n/a
Meas. Tech.
ChEMBL_839558 (CHEMBL2090365)
EC50
15±n/a nM
Citation
 Ginsburg-Shmuel, T; Haas, M; Grbic, D; Arguin, G; Nadel, Y; Gendron, FP; Reiser, G; Fischer, B UDP made a highly promising stable, potent, and selective P2Y6-receptor agonist upon introduction of a boranophosphate moiety. Bioorg Med Chem 20:5483-95 (2012) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 6
Synonyms:
P2RY6 | P2RY6_HUMAN | P2Y purinoceptor 6 | P2Y6 | Pyrimidinergic receptor P2Y6
Type:
PROTEIN
Mol. Mass.:
36452.29
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1511151
Residue:
328
Sequence:
MEWDNGTGQALGLPPTTCVYRENFKQLLLPPVYSAVLAAGLPLNICVITQICTSRRALTRTAVYTLNLALADLLYACSLPLLIYNYAQGDHWPFGDFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHKRGGRRAAWLVCVAVWLAVTTQCLPTAIFAATGIQRNRTVCYDLSPPALATHYMPYGMALTVIGFLLPFAALLACYCLLACRLCRQDGPAEPVAQERRGKAARMAVVVAAAFAISFLPFHITKTAYLAVRSTPGVPCTVLEAFAAAYKGTRPFASANSVLDPILFYFTQKKFRRRPHELLQKLTAKWQRQGR
  
Inhibitor
Name:
BDBM50403871
Synonyms:
URIDINE_DIPHOSPHATE
Type:
Small organic molecule
Emp. Form.:
C9H14N2O12P2
Mol. Mass.:
404.1612
SMILES:
O[C@@H]1[C@@H](CO[P@](O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O |r|
Structure:
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