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Target
Beta-2 adrenergic receptor
Ligand
BDBM60973
Substrate
n/a
Meas. Tech.
ChEBML_37826
Kd
0.891251±n/a nM
Citation
 IJzerman, AP; Aué, GH; Bultsma, T; Linschoten, MR; Timmerman, H Quantitative evaluation of the beta 2-adrenoceptor affinity of phenoxypropanolamines and phenylethanolamines. J Med Chem 28:1328-34 (1985) [PubMed]  Article 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2_BOVIN | Beta-2 adrenergic receptor | Beta-2 adrenoceptor | Beta-2 adrenoreceptor | adrenergic Beta
Type:
Enzyme Catalytic Domain
Mol. Mass.:
47141.18
Organism:
BOVINE
Description:
adrenergic Beta ADRB2 BOVINE::Q28044
Residue:
418
Sequence:
MGQPGNRSVFLLAPNASHAPDQNVTLERDEAWVVGMGILMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGACHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYLAITSPFKYQCLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRASHKEAINCYAKETCCDFFTNQPYAIASSIVSFYLPLVVMVFVYSRVFQVAKRQLQKIDKSEGRFHAQNVSQVEQDGRSGLGQRRTSKFYLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIKDNLIRKEIYILLNWLGYINSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGCSSNSNDRTDYTGEQSGYHLGEEKDSELLCEDPPGTENFVNQQGTVPSDSIDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM60973
Synonyms:
(2R)-1-(1-naphthalenyloxy)-3-(propan-2-ylamino)-2-propanol;hydrochloride | (2R)-1-(isopropylamino)-3-(1-naphthoxy)propan-2-ol;hydrochloride | (2R)-1-naphthalen-1-yloxy-3-(propan-2-ylamino)propan-2-ol;hydrochloride | (R)-(+)-Propranolol hydrochloride | MLS001333595 | SMR000875288 | cid_66366
Type:
Small organic molecule
Emp. Form.:
C16H21NO2
Mol. Mass.:
259.3434
SMILES:
CC(C)NC[C@@H](O)COc1cccc2ccccc12
Structure:
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