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Target
D(2) dopamine receptor
Ligand
BDBM50155606
Substrate
n/a
Meas. Tech.
ChEBML_60934
IC50
63±n/a nM
Citation
 Russell, MG; Baker, R; Billington, DC; Knight, AK; Middlemiss, DN; Noble, AJ Benz[f]isoquinoline analogues as high-affinity sigma ligands. J Med Chem 35:2025-33 (1992) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50155606
Synonyms:
3-Butyl-1,2,3,4,5,6-hexahydro-benzo[f]isoquinoline | CHEMBL188713 | CHEMBL541299
Type:
Small organic molecule
Emp. Form.:
C17H23N
Mol. Mass.:
241.3712
SMILES:
CCCCN1CCC2=C(CCc3ccccc23)C1 |t:7|
Structure:
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