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Target
Beta-2 adrenergic receptor
Ligand
BDBM82497
Substrate
n/a
Meas. Tech.
ChEMBL_38149 (CHEMBL651040)
EC50
3548±n/a nM
Citation
 Markovich, KM; Tantishaiyakul, V; Hamada, A; Miller, DD; Romstedt, KJ; Shams, G; Shin, Y; Fraundorfer, PF; Doyle, K; Feller, DR Synthesis of halogenated trimetoquinol derivatives and evaluation of their beta-agonist and thromboxane A2 (TXA2) antagonist activities. J Med Chem 35:466-79 (1992) [PubMed]  Article 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2_CAVPO | Adrb2 | adrenergic Beta2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
46993.24
Organism:
GUINEA PIG
Description:
adrenergic Beta2 ADRB2 GUINEA PIG::Q8K4Z4
Residue:
418
Sequence:
MGHLGNGSDFLLAPNASHAPDHNVTRERDEAWVVGMAIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMNMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWVVSGLTSFLPIQMHWYRATHKDAINCYAEETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAKKQLQKIDRSEGRFHTQNLSQVEQDGRSGHGLRRSSKFYLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSALKAYGNDCSSNSNGKTDYTGEPNVCHQGQEKERELLCEDPPGTEDLVSCPGTVPSDSIDSQGRNYSTNDSLL
  
Inhibitor
Name:
BDBM82497
Synonyms:
TMQ, R-(-)-8-Fluoro
Type:
Small organic molecule
Emp. Form.:
C19H22FNO5
Mol. Mass.:
363.3801
SMILES:
COc1cc(C[C@H]2NCCc3cc(O)c(O)c(F)c23)cc(OC)c1OC
Structure:
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