Reaction Details Report a problem with these data
Target
Somatostatin receptor type 2
Ligand
BDBM50423462
Substrate
n/a
Meas. Tech.
ChEMBL_461988 (CHEMBL944831)
Kd
6761±n/a nM
Citation
 Troxler, T; Enz, A; Hoyer, D; Langenegger, D; Neumann, P; Pfäffli, P; Schoeffter, P; Hurth, K Ergoline derivatives as highly potent and selective antagonists at the somatostatin sst 1 receptor. Bioorg Med Chem Lett 18:979-82 (2008) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 2
Synonyms:
SOMATOSTATIN SST2 | SRIF-1 | SS-2-R | SS2-R | SS2R | SSR2_HUMAN | SSTR2 | Somatostatin receptor type 2 (SSTR2)
Type:
Enzyme
Mol. Mass.:
41344.94
Organism:
Homo sapiens (Human)
Description:
P30874
Residue:
369
Sequence:
MDMADEPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFVVCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFIIIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFVVVLTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSRLNETTETQRTLLNGDLQTSI
  
Inhibitor
Name:
BDBM50423462
Synonyms:
CHEMBL251835
Type:
Small organic molecule
Emp. Form.:
C26H27BrN6O2
Mol. Mass.:
535.436
SMILES:
CN1C[C@@H](C[C@H]2[C@H]1Cc1c(Br)[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1ccc2nonc2c1
Structure:
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