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TargetMelatonin receptor
LigandBDBM50425200
Substrate/Competitorn/a
Meas. Tech.ChEMBL_937789
Ki 0.200000±n/a nM
Citation Morellato, LLefas-Le Gall, MLanglois, MCaignard, DHRenard, PDelagrange, PMathé-Allainmat, M Synthesis of new N-(arylcyclopropyl)acetamides and N-(arylvinyl)acetamides as conformationally-restricted ligands for melatonin receptors. Bioorg Med Chem Lett23:430-4 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Melatonin receptor
Name:Melatonin receptor
Synonyms:MTNR1B | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2)
Type:Enzyme
Mol. Mass.:40203.54
Organism:Homo sapiens (Human)
Description:P49286
Residue:362
Sequence:
MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLL
VILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVM
GLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGS
LEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRL
CLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFN
SCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQAD
AL
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  Blast E-value cutoff:
BDBM50425200
NameBDBM50425200
Synonyms:CHEMBL2314253
TypeSmall organic molecule
Emp. Form.C17H19NO3
Mol. Mass.285.3377
SMILESCOc1ccc2ccc(OC)c([C@@H]3C[C@H]3NC(C)=O)c2c1 |r|
Structure
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n/a