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Target
Galectin-1
Ligand
BDBM50425516
Substrate
n/a
Meas. Tech.
ChEMBL_936060 (CHEMBL2319302)
Kd
180000±n/a nM
Citation
 van Hattum, H; Branderhorst, HM; Moret, EE; Nilsson, UJ; Leffler, H; Pieters, RJ Tuning the preference of thiodigalactoside- and lactosamine-based ligands to galectin-3 over galectin-1. J Med Chem 56:1350-4 (2013) [PubMed]  Article 
Target
Name:
Galectin-1
Synonyms:
14 kDa lectin | Galaptin | HPL | LEG1_HUMAN | LGALS1 | Lactose-binding lectin 1 | Lectin galactoside-binding soluble 1 | Putative MAPK-activating protein PM12
Type:
beta galactoside-binding protein
Mol. Mass.:
14713.53
Organism:
Homo sapiens (Human)
Description:
P09382
Residue:
135
Sequence:
MACGLVASNLNLKPGECLRVRGEVAPDAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIVCNSKDGGAWGTEQREAVFPFQPGSVAEVCITFDQANLTVKLPDGYEFKFPNRLNLEAINYMAADGDFKIKCVAFD
  
Inhibitor
Name:
BDBM50425516
Synonyms:
CHEMBL2313336
Type:
Small organic molecule
Emp. Form.:
C35H42N4O12
Mol. Mass.:
710.7276
SMILES:
OC[C@H]1O[C@@H](O[C@@H]2[C@@H](CO)O[C@@H](OCCCN=[N+]=[N-])[C@H](NC(=O)c3ccccc3)[C@H]2O)[C@H](O)[C@@H](OCc2ccc(Oc3ccccc3)cc2)[C@H]1O |r|
Structure:
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