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TargetHisto-blood group ABO system transferase
LigandBDBM50427444
Substrate/Competitorn/a
Meas. Tech.ChEMBL_941221
IC50 1600000±n/a nM
Citation Schaefer, KSindhuwinata, NHackl, TKötzler, MPNiemeyer, FCPalcic, MMPeters, TMeyer, B A nonionic inhibitor with high specificity for the UDP-Gal donor binding site of human blood group B galactosyltransferase: design, synthesis, and characterization. J Med Chem56:2150-4 (2013) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Histo-blood group ABO system transferase
Name:Histo-blood group ABO system transferase
Synonyms:A transferase | ABO | B transferase | Fucosylglycoprotein 3-alpha-galactosyltransferase | Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase | Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase soluble form | Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase | Glycoprotein-fucosylgalactoside alpha-galactosyltransferase | Histo-blood group A transferase | Histo-blood group B transferase | NAGAT
Type:PROTEIN
Mol. Mass.:40947.46
Organism:Homo sapiens
Description:ChEMBL_941222
Residue:354
Sequence:
MAEVLRTLAGKPKCHALRPMILFLIMLVLVLFGYGVLSPRSLMPGSLERGFCMAVREPDH
LQRVSLPRMVYPQPKVLTPCRKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTV
FAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVRAYKR
WQDVSMRRMEMISDFCERRFLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPGFYGSS
REAFTYERRPQSQAYIPKDEGDFYYLGGFFGGSVQEVQRLTRACHQAMMVDQANGIEAVW
HDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVPKNHQAVRNP
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50427444
n/a
NameBDBM50427444
Synonyms:CHEMBL2326313
TypeSmall organic molecule
Emp. Form.C16H24N4O12
Mol. Mass.464.3814
SMILESOC[C@H]1O[C@H](OC[C@@H](O)[C@@H](O)[C@H](O)Cn2c3[nH]c(=O)[nH]c(=O)c3[nH]c2=O)[C@H](O)[C@@H](O)[C@H]1O |r|
Structure
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