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Target
Carbonic anhydrase 14
Ligand
BDBM92712
Substrate
n/a
Meas. Tech.
ChEMBL_942101 (CHEMBL2340799)
Ki
6500±n/a nM
Citation
 Carta, F; Vullo, D; Maresca, A; Scozzafava, A; Supuran, CT Mono-/dihydroxybenzoic acid esters and phenol pyridinium derivatives as inhibitors of the mammalian carbonic anhydrase isoforms I, II, VII, IX, XII and XIV. Bioorg Med Chem 21:1564-9 (2013) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 14
Synonyms:
CA-XIV | CA14 | CAH14_HUMAN | Carbonate dehydratase XIV | Carbonic Anhydrase XIV | Carbonic anhydrase | Carbonic anhydrase 14 | Carbonic anhydrase 14 (CA XIV) | Carbonic anhydrase XIV (CA XIV)
Type:
Enzyme
Mol. Mass.:
37665.67
Organism:
Homo sapiens (Human)
Description:
Human (cloned) isozyme.
Residue:
337
Sequence:
MLFSALLLEVIWILAADGGQHWTYEGPHGQDHWPASYPECGNNAQSPIDIQTDSVTFDPDLPALQPHGYDQPGTEPLDLHNNGHTVQLSLPSTLYLGGLPRKYVAAQLHLHWGQKGSPGGSEHQINSEATFAELHIVHYDSDSYDSLSEAAERPQGLAVLGILIEVGETKNIAYEHILSHLHEVRHKDQKTSVPPFNLRELLPKQLGQYFRYNGSLTTPPCYQSVLWTVFYRRSQISMEQLEKLQGTLFSTEEEPSKLLVQNYRALQPLNQRMVFASFIQAGSSYTTGEMLSLGVGILVGCLCLLLAVYFIARKIRKKRLENRKSVVFTSAQATTEA
  
Inhibitor
Name:
BDBM92712
Synonyms:
2,6-Dihydroxybenzoate, VII
Type:
Small molecule
Emp. Form.:
C7H6O4
Mol. Mass.:
154.1201
SMILES:
OC(=O)c1c(O)cccc1O
Structure:
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