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Target
Carbonic anhydrase 7
Ligand
BDBM50428797
Substrate
n/a
Meas. Tech.
ChEMBL_949342 (CHEMBL2339340)
Ki
>200000±n/a nM
Citation
 Gavernet, L; Gonzalez Funes, JL; Palestro, PH; Bruno Blanch, LE; Estiu, GL; Maresca, A; Barrios, I; Supuran, CT Inhibition pattern of sulfamide-related compounds in binding to carbonic anhydrase isoforms I, II, VII, XII and XIV. Bioorg Med Chem 21:1410-8 (2013) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 7
Synonyms:
CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII)
Type:
Enzyme
Mol. Mass.:
29664.11
Organism:
Homo sapiens (Human)
Description:
Human cloned isozyme.
Residue:
264
Sequence:
MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNNFRPPQPLKGRVVKASFRA
  
Inhibitor
Name:
BDBM50428797
Synonyms:
CHEMBL2335234
Type:
Small organic molecule
Emp. Form.:
C9H18N2O6S
Mol. Mass.:
282.314
SMILES:
COC(=O)[C@H](C)NS(=O)(=O)NC(=O)OC(C)(C)C |r|
Structure:
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