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Target
D-amino-acid oxidase
Ligand
BDBM50431065
Substrate
n/a
Meas. Tech.
ChEMBL_947855 (CHEMBL2343131)
IC50
4.4±n/a nM
Citation
 Hondo, T; Warizaya, M; Niimi, T; Namatame, I; Yamaguchi, T; Nakanishi, K; Hamajima, T; Harada, K; Sakashita, H; Matsumoto, Y; Orita, M; Takeuchi, M 4-Hydroxypyridazin-3(2H)-one derivatives as novel D-amino acid oxidase inhibitors. J Med Chem 56:3582-92 (2013) [PubMed]  Article 
Target
Name:
D-amino-acid oxidase
Synonyms:
DAAO | DAMOX | Dao | Dao1 | OXDA_MOUSE
Type:
PROTEIN
Mol. Mass.:
38667.41
Organism:
Mus musculus
Description:
ChEMBL_947855
Residue:
345
Sequence:
MRVAVIGAGVIGLSTALCIHERYHPTQPLHMKIYADRFTPFTTSDVAAGLWQPYLSDPSNPQEAEWSQQTFDYLLSCLHSPNAEKMGLALISGYNLFRDEVPDPFWKNAVLGFRKLTPSEMDLFPDYGYGWFNTSLLLEGKSYLPWLTERLTERGVKLIHRKVESLEEVARGVDVIINCTGVWAGALQADASLQPGRGQIIQVEAPWIKHFILTHDPSLGIYNSPYIIPGSKTVTLGGIFQLGNWSGLNSVRDHNTIWKSCCKLEPTLKNARIVGELTGFRPVRPQVRLEREWLRHGSSSAEVIHNYGHGGYGLTIHWGCAMEAANLFGKILEEKKLSRLPPSHL
  
Inhibitor
Name:
BDBM50431065
Synonyms:
CHEMBL2338799 | US10202399, Example 16
Type:
Small organic molecule
Emp. Form.:
C13H14N2O3
Mol. Mass.:
246.2619
SMILES:
COc1cccc(CCc2cc(O)c(=O)[nH]n2)c1
Structure:
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