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TargetBeta-3 adrenergic receptor
LigandBDBM25748
Substrate/Competitorn/a
Meas. Tech.ChEMBL_952272
EC50 10000±n/a nM
Citation Mistry, SNBaker, JGFischer, PMHill, SJGardiner, SMKellam, B Synthesis and in vitro and in vivo characterization of highlyß1-selectiveß-adrenoceptor partial agonists. J Med Chem56:3852-65 (2013) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Beta-3 adrenergic receptor
Name:Beta-2 adrenergic receptor and beta-3 adrenergic receptor
Synonyms:ADRB3 | B3AR | Beta-3 adrenoceptor | Beta-3 adrenoreceptor | adrenergic Beta3
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:43534.88
Organism:Homo sapiens (Human)
Description:n/a
Residue:408
Sequence:
MAPWPHENSSLAPWPDLPTLAPNTANTSGLPGVPWEAALAGALLALAVLATVGGNLLVIV
AIAWTPRLQTMTNVFVTSLAAADLVMGLLVVPPAATLALTGHWPLGATGCELWTSVDVLC
VTASIETLCALAVDRYLAVTNPLRYGALVTKRCARTAVVLVWVVSAAVSFAPIMSQWWRV
GADAEAQRCHSNPRCCAFASNMPYVLLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRG
ELGRFPPEESPPAPSRSLAPAPVGTCAPPEGVPACGRRPARLLPLREHRALCTLGLIMGT
FTLCWLPFFLANVLRALGGPSLVPGPAFLALNWLGYANSAFNPLIYCRSPDFRSAFRRLL
CRCGRRLPPEPCAAARPALFPSGVPAARSSPAQPRLCQRLDGASWGVS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM25748
NameBDBM25748
Synonyms:3-(2-{[3-(2-cyanophenoxy)-2-hydroxypropyl]amino}ethyl)-1-phenylurea | ICI 89,406 | ICI 89406
TypeSmall organic molecule
Emp. Form.C19H22N4O3
Mol. Mass.354.403
SMILESOC(CNCCNC(=O)Nc1ccccc1)COc1ccccc1C#N
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a