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Target
Matrilysin
Ligand
BDBM50433867
Substrate
n/a
Meas. Tech.
ChEMBL_959635 (CHEMBL2382705)
Ki
>25000±n/a nM
Citation
 Jin, Y; Roycik, MD; Bosco, DB; Cao, Q; Constantino, MH; Schwartz, MA; Sang, QX Matrix metalloproteinase inhibitors based on the 3-mercaptopyrrolidine core. J Med Chem 56:4357-73 (2013) [PubMed]  Article 
Target
Name:
Matrilysin
Synonyms:
MMP7 | MMP7_HUMAN | MPSL1 | Matrix metalloproteinase 7 | Matrix metalloproteinase-7 (MMP-7) | Matrix metalloproteinase-7 (MMP7) | PUMP1
Type:
Enzyme
Mol. Mass.:
29681.54
Organism:
Homo sapiens (Human)
Description:
P09237
Residue:
267
Sequence:
MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLKEMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGDPQNFKLSQDDIKGIQKLYGKRSNSRKK
  
Inhibitor
Name:
BDBM50433867
Synonyms:
CHEMBL2380401
Type:
Small organic molecule
Emp. Form.:
C18H21N3O4S2
Mol. Mass.:
407.507
SMILES:
CN([C@H]1CN(C[C@@H]1S)C(N)=O)S(=O)(=O)c1ccc(Oc2ccccc2)cc1 |r|
Structure:
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