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Target
P2Y purinoceptor 1
Ligand
BDBM50435007
Substrate
n/a
Meas. Tech.
ChEMBL_963102 (CHEMBL2390581)
EC50
4.5±n/a nM
Citation
 Azran, S; Förster, D; Danino, O; Nadel, Y; Reiser, G; Fischer, B Highly efficient biocompatible neuroprotectants with dual activity as antioxidants and P2Y receptor agonists. J Med Chem 56:4938-52 (2013) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 1
Synonyms:
ATP receptor | P2RY1_RAT | P2Y1 | P2ry1 | Purinergic receptor | Purinergic receptor P2Y1
Type:
PROTEIN
Mol. Mass.:
42338.46
Organism:
Rattus norvegicus
Description:
ChEMBL_873671
Residue:
373
Sequence:
MTEVPWSAVPNGTDAAFLAGLGSLWGNSTIASTAAVSSSFRCALIKTGFQFYYLPAVYILVFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDVMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAIYVSVLVWLIVVVAISPILFYSGTGIRKNKTVTCYDSTSDEYLRSYFIYSMCTTVAMFCIPLVLILGCYGLIVRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPEMCDFNDRVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEEMTLNILSEFKQNGDTSL
  
Inhibitor
Name:
BDBM50435007
Synonyms:
CHEMBL2386493
Type:
Small organic molecule
Emp. Form.:
C10H16BClN5O12P3
Mol. Mass.:
537.446
SMILES:
B[P@@](=O)(OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(Cl)nc12)OP(O)(=O)OP(O)(O)=O |r|
Structure:
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