Reaction Details Report a problem with these data
Target
Acetylpolyamine amidohydrolase
Ligand
BDBM50438384
Substrate
n/a
Meas. Tech.
ChEMBL_975718 (CHEMBL2415216)
IC50
230000±n/a nM
Citation
 Decroos, C; Bowman, CM; Christianson, DW Synthesis and evaluation of N8-acetylspermidine analogues as inhibitors of bacterial acetylpolyamine amidohydrolase. Bioorg Med Chem 21:4530-40 (2013) [PubMed]  Article 
Target
Name:
Acetylpolyamine amidohydrolase
Synonyms:
APAH_MYCRA | Acetylpolyamine amidohydrolase (APAH) | Acetylpolyamine aminohydrolase | aph | aphA
Type:
Protein
Mol. Mass.:
36324.64
Organism:
Mycoplana ramosa (Gram-negative bacterium)
Description:
n/a
Residue:
341
Sequence:
MRVIFSEDHKLRNAKTELYGGELVPPFEAPFRAEWILAAVKEAGFDDVVAPARHGLETVLKVHDAGYLNFLETAWDRWKAAGYKGEAIATSFPVRRTSPRIPTDIEGQIGYYCNAAETAISPGTWEAALSSMASAIDGADLIAAGHKAAFSLCRPPGHHAGIDMFGGYCFINNAAVAAQRLLDKGAKKIAILDVDFHHGNGTQDIFYERGDVFFASLHGDPAEAFPHFLGYAEETGKGAGAGTTANYPMGRGTPYSVWGEALTDSLKRIAAFGAEAIVVSLGVDTFEQDPISFFKLTSPDYITMGRTIAASGVPLLVVMEGGYGVPEIGLNVANVLKGVAG
  
Inhibitor
Name:
BDBM50438384
Synonyms:
CHEMBL2414006
Type:
Small organic molecule
Emp. Form.:
C8H21BN2O2
Mol. Mass.:
188.076
SMILES:
NCCCNCCCCCB(O)O
Structure:
Search PDB for entries with ligand similarity: