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Target
Tumor necrosis factor receptor superfamily member 6
Ligand
BDBM42662
Substrate
n/a
Meas. Tech.
ChEMBL_979855 (CHEMBL2422398)
EC50
692±n/a nM
Citation
 Jung, SH; Suh, JH; Kim, EH; Kim, JT; Yoo, SE; Kang, NS The discovery of inhibitors of Fas-mediated cell death pathway using the combined computational method. Bioorg Med Chem Lett 23:5155-64 (2013) [PubMed]  Article 
Target
Name:
Tumor necrosis factor receptor superfamily member 6
Synonyms:
Apo-1 antigen | Apoptosis-mediating surface antigen FAS | Apt1 | CD_antigen=CD95 | FASLG receptor | Fas | TNR6_RAT | Tnfrsf6
Type:
PROTEIN
Mol. Mass.:
36836.00
Organism:
Rattus norvegicus
Description:
ChEMBL_107643
Residue:
324
Sequence:
MLWIMAVLPLVLAGPELNVRMQGTDSIFEGLELKRSVRETDNNCSEGLYQVGPFCCQPCQPGERKVKDCTTSGGAPTCHPCTEGEEYTDRKHYSDKCRRCAFCDEGHGLEVETNCTRTQNTKCRCKENFYCNASLCDHCYHCTSCGLEDILEPCTRTSNTKCKKQSSNYKLLWLLILPGLAILFVFIYKRYRKRQPGDPESGIPSPESVPMNVSDVNLNKYIWRTAEKMKICDAKKFARQHKIPESKIDEIEHNSPQDAAEQKIQLLQCWYQSHGKTGACQALIQGLRKANRCDIAEEIQAMVWEDHENSISNSRNENEGQSLE
  
Inhibitor
Name:
BDBM42662
Synonyms:
2-[[1-oxo-2-(2-pyridinylthio)ethyl]amino]benzoic acid methyl ester | 2-[[2-(2-pyridylthio)acetyl]amino]benzoic acid methyl ester | MLS000080601 | SMR000034995 | cid_667093 | methyl 2-(2-pyridin-2-ylsulfanylethanoylamino)benzoate | methyl 2-[(2-pyridin-2-ylsulfanylacetyl)amino]benzoate
Type:
Small organic molecule
Emp. Form.:
C15H14N2O3S
Mol. Mass.:
302.348
SMILES:
COC(=O)c1ccccc1NC(=O)CSc1ccccn1
Structure:
Search PDB for entries with ligand similarity: