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TargetLethal(3)malignant brain tumor-like protein 4
LigandBDBM50440605
Substrate/Competitorn/a
Meas. Tech.ChEMBL_983407
IC50>10000±n/a nM
Citation James, LIKorboukh, VKKrichevsky, LBaughman, BMHerold, JMNorris, JLJin, JKireev, DBJanzen, WPArrowsmith, CHFrye, SV Small-molecule ligands of methyl-lysine binding proteins: optimization of selectivity for L3MBTL3. J Med Chem56:7358-71 (2013) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Lethal(3)malignant brain tumor-like protein 4
Name:Lethal(3)malignant brain tumor-like protein 4
Synonyms:H-l(3)mbt-like protein 4 | L(3)mbt-like protein 4
Type:PROTEIN
Mol. Mass.:71132.81
Organism:Homo sapiens (Human)
Description:ChEMBL_983407
Residue:623
Sequence:
MKQPNRKRKLNMDSKERLDQDGRLEQAEEEKKPKDSTTPLSHVPSAAAQGAWSWEWYLKE
QKAVAAPVELFSKDQSFPEHENGFQIGMRLEGIDPRHPSVFCVLSVAEVCGYRLRLHFDG
YLSCYDFWTNAGSPDIHPVGWCEKTKHELHIPKGYRKDKFVWMDYLKACKLQNAPKKLFR
NRSPNGPMSKEFQVGMKLEAVDRKNPSLVCVATIADIVEDRLLVHFDNWDDSYDYWCDVN
SPYVQPVGWCQENGRTLIAPQGYPNPENFSWTEYLEATQTNAVPAKVFKMRLPHGFLPNM
KLEVVDKRNPRLIRVATIVDVDDQRVKVHFDGWDHKYDYWVEADSPDIHPIGWCDVTGHP
LEVPQRTNDLKILPGQAVCPTPGCRGIGHIRGPRYSGHHSAFGCPYSDMNLKKEATLHDR
LREQTQANLESDSSHSKSKSLCSLNFNGKHEKVNSQPRLVQQAKCLKIKGKEDIDLDNLF
RVLVLHPRGLEYSVEQAQQVLHQSVSMSTVSAHPFRDLPLGREQHCKLLPGVADIRASQV
ARWTVDEVAEFVQSLLGCEEHAKCFKKEQIDGKAFLLLTQTDIVKVMKIKLGPALKIYNS
ILMFRHSQELPEEDIASGQEVRG
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50440605
NameBDBM50440605
Synonyms:CHEMBL2424677
TypeSmall organic molecule
Emp. Form.C33H39N5O2
Mol. Mass.537.6951
SMILESCCN1Cc2ccc(NC(=O)c3ccc(C(=O)N4CCC(CC4)C4CCCN4)c(Nc4ccccc4)c3)cc2C1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
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