Reaction Details Report a problem with these data
Target
Baculoviral IAP repeat-containing protein 5
Ligand
BDBM50442671
Substrate
n/a
Meas. Tech.
ChEMBL_989058 (CHEMBL2445688)
IC50
25000±n/a nM
Citation
 Ho, SS; Go, ML Restraining the flexibility of the central linker in terameprocol results in constrained analogs with improved growth inhibitory activity. Bioorg Med Chem Lett 23:6127-33 (2013) [PubMed]  Article 
Target
Name:
Baculoviral IAP repeat-containing protein 5
Synonyms:
API4 | Apoptosis inhibitor 4 | Apoptosis inhibitor survivin | BIRC5 | BIRC5_HUMAN | IAP4
Type:
PROTEIN
Mol. Mass.:
16386.52
Organism:
Homo sapiens (Human)
Description:
ChEMBL_443470
Residue:
142
Sequence:
MGAPTLPPAWQPFLKDHRISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDDDPIEEHKKHSSGCAFLSVKKQFEELTLGEFLKLDRERAKNKIAKETNNKKKEFEETAKKVRRAIEQLAAMD
  
Inhibitor
Name:
BDBM50442671
Synonyms:
CHEMBL2442083
Type:
Small organic molecule
Emp. Form.:
C40H70N4O4
Mol. Mass.:
671.0082
SMILES:
CCN(CC)CCOc1ccc(CCCCc2ccc(OCCN(CC)CC)c(OCCN(CC)CC)c2)cc1OCCN(CC)CC
Structure:
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