Reaction Details Report a problem with these data
Target
Arginase
Ligand
BDBM84978
Substrate
n/a
Meas. Tech.
ChEMBL_1286565 (CHEMBL3110798)
IC50
12200±n/a nM
Citation
 de Sousa, LR; Ramalho, SD; Burger, MC; Nebo, L; Fernandes, JB; da Silva, MF; Iemma, MR; Corrêa, CJ; de Souza, DH; Lima, MI; Vieira, PC Isolation of arginase inhibitors from the bioactivity-guided fractionation of Byrsonima coccolobifolia leaves and stems. J Nat Prod 77:392-6 (2014) [PubMed]  Article 
Target
Name:
Arginase
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
36149.67
Organism:
Leishmania amazonensis
Description:
ChEMBL_107995
Residue:
329
Sequence:
MEHVQQYKFYKEKKMSIVLAPFSGGQPHSGVELGPDYLLKQGLQQDMEKLGWDTRLERVFDGKVVEARKASDNGDRIGRVKRPRLTAECTEKIYKCVRRVAEQGRFPLTIGGDHSIALGTVAGVLSVHPDAGVIWVDAHADINTMSGTVSGNLHGCPLSILLGLDRENIPECFSWVPQVLKPNKIAYIGLRAVDDEEKKILHDLNIAAFSMHHVDRYGIDKVVSMAIEAVSPKGTEPVMVSYDVDTIDPLYVPATGTPVRGGLSFREALFLCERIAECGRLVALDVVECNPLLAATESHVNDTISDGRAIARCMMGETLLYTPHTSSKL
  
Inhibitor
Name:
BDBM84978
Synonyms:
Quercitrin | cid_5280459
Type:
Small organic molecule
Emp. Form.:
C21H20O11
Mol. Mass.:
448.3769
SMILES:
C[C@@H]1O[C@@H](Oc2c(O)c3c(cc(O)cc3=O)oc2-c2ccc(O)c(O)c2)[C@H](O)[C@H](O)[C@H]1O
Structure:
Search PDB for entries with ligand similarity: