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Target
Adenosine receptor A2a
Ligand
BDBM50049387
Substrate
n/a
Meas. Tech.
ChEMBL_30279 (CHEMBL640100)
Ki
35481±n/a nM
Citation
 Moro, S; van Rhee, AM; Sanders, LH; Jacobson, KA Flavonoid derivatives as adenosine receptor antagonists: a comparison of the hypothetical receptor binding site based on a comparative molecular field analysis model. J Med Chem 41:46-52 (1998) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
AA2AR_RAT | ADENOSINE A2a | Adenosine A2 receptor | Adenosine A2a receptor (A2a) | Adenosine Receptors A2a (A2a) | Adenosine receptor A2a and A3 | Adenosine receptors A2a | Adora2a | Rat striatal adenosine A2a receptor
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
45015.65
Organism:
Rattus norvegicus (rat)
Description:
Rat A2A receptors expressed in CHO cells.
Residue:
410
Sequence:
MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS
  
Inhibitor
Name:
BDBM50049387
Synonyms:
5,4'-Dihydroxy-7-o-methoxyflavanone | 5-Hydroxy-2-(4-hydroxy-phenyl)-7-methoxy-chroman-4-one | 5-hydroxy-2-(4-hydroxyphenyl)-7-methoxychroman-4-one | CHEMBL74852 | NSC-407228
Type:
Small organic molecule
Emp. Form.:
C16H14O5
Mol. Mass.:
286.2794
SMILES:
COc1cc(O)c2C(=O)CC(Oc2c1)c1ccc(O)cc1
Structure:
Search PDB for entries with ligand similarity: