Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50049387
Substrate
n/a
Meas. Tech.
ChEMBL_30324 (CHEMBL638578)
Ki
3388±n/a nM
Citation
 Moro, S; van Rhee, AM; Sanders, LH; Jacobson, KA Flavonoid derivatives as adenosine receptor antagonists: a comparison of the hypothetical receptor binding site based on a comparative molecular field analysis model. J Med Chem 41:46-52 (1998) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50049387
Synonyms:
5,4'-Dihydroxy-7-o-methoxyflavanone | 5-Hydroxy-2-(4-hydroxy-phenyl)-7-methoxy-chroman-4-one | 5-hydroxy-2-(4-hydroxyphenyl)-7-methoxychroman-4-one | CHEMBL74852 | NSC-407228
Type:
Small organic molecule
Emp. Form.:
C16H14O5
Mol. Mass.:
286.2794
SMILES:
COc1cc(O)c2C(=O)CC(Oc2c1)c1ccc(O)cc1
Structure:
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