Target
Indolethylamine N-methyltransferase
Ligand
BDBM50000321
Substrate
n/a
Meas. Tech.
ChEMBL_1333667 (CHEMBL3231053)
IC50
6200±n/a nM
Citation
 Rokach, JHamel, PHunter, NRReader, GRooney, CSAnderson, PSCragoe, EJMandel, LR Cyclic amidine inhibitors of indolamine N-methyltransferase. J Med Chem 22:237-47 (1979) [PubMed]  Article 
Target
Name:
Indolethylamine N-methyltransferase
Synonyms:
Amine N-methyltransferase | Aromatic alkylamine N-methyltransferase | Arylamine N-methyltransferase | INMT | INMT_RABIT | Indolamine N-methyltransferase | Thioether S-methyltransferase
Type:
PROTEIN
Mol. Mass.:
28949.17
Organism:
Oryctolagus cuniculus
Description:
ChEMBL_108264
Residue:
263
Sequence:
MEGGFTGGDEYQKHFLPRDYLNTYYSFQSGPSPEAEMLKFNLECLHKTFGPGGLQGDTLIDIGSGPTIYQVLAACESFKDITLSDFTDRNREELAKWLKKEPGAYDWTPALKFACELEGNSGRWQEKAEKLRATVKRVLKCDANLSNPLTPVVLPPADCVLTLLAMECACCSLDAYRAALRNLASLLKPGGHLVTTVTLQLSSYMVGEREFSCVALEKEEVEQAVLDAGFDIEQLLYSPQSYSASTAPNRGVCFLVARKKPGS
  
Inhibitor
Name:
BDBM50000321
Synonyms:
CHEMBL3228397
Type:
Small organic molecule
Emp. Form.:
C8H11N3O4
Mol. Mass.:
213.1906
SMILES:
OC(=O)C(O)=O.Cn1c(N)cccc1=N
Structure:
Search PDB for entries with ligand similarity: