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TargetApelin
LigandBDBM50009575
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1336421
Ki 0.04±n/a nM
Citation Margathe, JFIturrioz, XAlvear-Perez, RMarsol, CRiché, SChabane, HTounsi, NKuhry, MHeissler, DHibert, MLlorens-Cortes, CBonnet, D Structure-activity relationship studies toward the discovery of selective apelin receptor agonists. J Med Chem57:2908-19 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Apelin
Name:Apelin
Synonyms:APEL | APJ endogenous ligand | APLN | Apelin-13 | Apelin-28 | Apelin-31 | Apelin-36
Type:PROTEIN
Mol. Mass.:8579.06
Organism:Homo sapiens (Human)
Description:ChEMBL_108275
Residue:77
Sequence:
MNLRLCVQALLLLWLSLTAVCGGSLMPLPDGNGLEDGNVRHLVQPRGSRNGPGPWQGGRR
KFRRQRPRLSHKGPMPF
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50009575
NameBDBM50009575
Synonyms:CHEMBL3234446
TypeSmall organic molecule
Emp. Form.C96H156N34O20S
Mol. Mass.2138.547
SMILESCSCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(O)=O |r|
Structure
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