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Target
Arylamine N-acetyltransferase 2
Ligand
BDBM50014913
Substrate
n/a
Meas. Tech.
ChEMBL_1347892 (CHEMBL3267128)
IC50
89000±n/a nM
Citation
 Egleton, JE; Thinnes, CC; Seden, PT; Laurieri, N; Lee, SP; Hadavizadeh, KS; Measures, AR; Jones, AM; Thompson, S; Varney, A; Wynne, GM; Ryan, A; Sim, E; Russell, AJ Structure-activity relationships and colorimetric properties of specific probes for the putative cancer biomarker human arylamine N-acetyltransferase 1. Bioorg Med Chem 22:3030-54 (2014) [PubMed]  Article 
Target
Name:
Arylamine N-acetyltransferase 2
Synonyms:
AAC2 | ARY2_MESAU | AT-2 | Arylamide acetylase 2 | N-acetyltransferase type 2 | NAT-2 | NAT2 | PNAT | Polymorphic arylamine N-acetyltransferase
Type:
PROTEIN
Mol. Mass.:
33829.75
Organism:
Mesocricetus auratus
Description:
ChEMBL_108305
Residue:
290
Sequence:
MDIEAYFERIGYQNSRNKLDLQTLTEILQHQIRAIPFENLNIHCGESMELSLETIFDQIVRKKRGGWCLQVNHLLYWALTKMGFETTMLGGYVFNTPANKYSSGMIHLLVQVTISDRNYIVDAGFGRSLQMWEPLELVSGKDHPQVPAIFRLTEENETWYLDQIRREQYVPNQAFVNSDLLEKNKYRKIYSFTLEPRTIEDFESMNTYLQTSPASVFTSKSFCSLQTPEGVHCLVGCTLTYRRFSYKDNVDLVEFKSLKEEEIEDVLKTIFGISLEKKLVPKHGDRFFTI
  
Inhibitor
Name:
BDBM50014913
Synonyms:
CHEMBL3262048
Type:
Small organic molecule
Emp. Form.:
C24H20N2O4S
Mol. Mass.:
432.492
SMILES:
Cc1cc(C)cc(NC2=C(NS(=O)(=O)c3ccccc3)C(=O)c3ccccc3C2=O)c1 |c:8|
Structure:
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