Reaction Details Report a problem with these data
Target
Delta-aminolevulinic acid dehydratase
Ligand
BDBM50017194
Substrate
n/a
Meas. Tech.
ChEMBL_1365593 (CHEMBL3297374)
IC50
500000±n/a nM
Citation
 Lentz, CS; Halls, VS; Hannam, JS; Strassel, S; Lawrence, SH; Jaffe, EK; Famulok, M; Hoerauf, A; Pfarr, KM wALADin benzimidazoles differentially modulate the function of porphobilinogen synthase orthologs. J Med Chem 57:2498-510 (2014) [PubMed]  Article 
Target
Name:
Delta-aminolevulinic acid dehydratase
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
36671.06
Organism:
Wolbachia sp. subsp. Brugia malayi (strain TRS)
Description:
ChEMBL_108383
Residue:
331
Sequence:
MMFNFPNTRLRRRRSSKWVRNLTSESALSVNDLIFPLFVHDREETTELVSSLPGMKCYSIDGLVSIAQEAEDLGINAVAIFPVVDSKLKSENAEEAYNSDNLICKAIRAIKLKVPGIGIIADVALDPYTTHGHDGILKSNQIDVENDKTVSILCKQALALAKAGCNIVASSDMMDGRVGRIRKVLDDNNLQDVSILSYAVKYCSSFYAPFRQIVGSCVSSNSIDKSGYQMDYRNAREAICEIEMDLNEGADFIMVKPGMPYLDIIKMASDEFNFPIFAYQVSGEYAMIKAATNNGWLDYDKVIYESLVGFKRAGASAIFTYAALDVAKNLR
  
Inhibitor
Name:
BDBM50017194
Synonyms:
CHEMBL1774061
Type:
Small organic molecule
Emp. Form.:
C8H6N2O2
Mol. Mass.:
162.1454
SMILES:
OC(=O)c1ccc2[nH]cnc2c1
Structure:
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