Reaction Details Report a problem with these data
Target
Delta-aminolevulinic acid dehydratase, chloroplastic
Ligand
BDBM50017192
Substrate
n/a
Meas. Tech.
ChEMBL_1365592 (CHEMBL3297373)
IC50
155000±n/a nM
Citation
 Lentz, CS; Halls, VS; Hannam, JS; Strassel, S; Lawrence, SH; Jaffe, EK; Famulok, M; Hoerauf, A; Pfarr, KM wALADin benzimidazoles differentially modulate the function of porphobilinogen synthase orthologs. J Med Chem 57:2498-510 (2014) [PubMed]  Article 
Target
Name:
Delta-aminolevulinic acid dehydratase, chloroplastic
Synonyms:
ALAD | ALADH | HEM2_PEA | HEMB
Type:
PROTEIN
Mol. Mass.:
43811.42
Organism:
Pisum sativum
Description:
ChEMBL_108384
Residue:
398
Sequence:
HTFVDLKSPFTLSNYLSFSSSKRRQPPSLFTVRASDSDFEAAVVAGKVPEAPPVPPTPASPAGTPVVPSLPIQRRPRRNRRSPALRSAFQETTLSPANFVYPLFIHEGEEDTPIGAMPGCYRLGWRHGLLEEVAKARDVGVNSVVLFPKIPDALKTPTGDEAYNEDGLVPRSIRLLKDKYPDLIIYTDVALDPYSSDGHDGIVREDGVIMNDETVHQLCKQAVAQARAGADVVSPSDMMDGRVGAMRVALDAEGFQHVSIMSYTAKYASSFYGPFREALDSNPRFGDKKTYQMNPANYREALTEMREDESEGADILLVKPGLPYLDIIRLLRDNSPLPIAAYQVSGEYSMIKAGGALKMIDEEKVMMESLLCLRRAGADIILTYFALQAARTLCGEKR
  
Inhibitor
Name:
BDBM50017192
Synonyms:
CHEMBL3287368
Type:
Small organic molecule
Emp. Form.:
C16H14N2O3
Mol. Mass.:
282.294
SMILES:
COc1cccc(Cn2cnc3cc(ccc23)C(O)=O)c1
Structure:
Search PDB for entries with ligand similarity: