Reaction Details Report a problem with these data
Target
Cytosol aminopeptidase [33-68,L62W]
Ligand
BDBM50025047
Substrate
n/a
Meas. Tech.
ChEMBL_1442056 (CHEMBL3373424)
Ki
213±n/a nM
Citation
 Vassiliou, S; Weglarz-Tomczak, E; Berlicki, L; Pawelczak, M; Nocek, B; Mulligan, R; Joachimiak, A; Mucha, A Structure-guided, single-point modifications in the phosphinic dipeptide structure yield highly potent and selective inhibitors of neutral aminopeptidases. J Med Chem 57:8140-51 (2014) [PubMed]  Article 
Target
Name:
Cytosol aminopeptidase [33-68,L62W]
Synonyms:
AMPL_PIG | Cytosol aminopeptidase | LAP3 | Leucine aminopeptidase (LAP)
Type:
Enzyme
Mol. Mass.:
4015.44
Organism:
Sus scrofa (Pig)
Description:
P28839[33-68,L62W]
Residue:
36
Sequence:
TKGLVLGIYSKEKEDDAPQFTSAGENFDKWVSGKLR
  
Inhibitor
Name:
BDBM50025047
Synonyms:
CHEMBL3355100
Type:
Small organic molecule
Emp. Form.:
C21H28NO4P
Mol. Mass.:
389.4251
SMILES:
Cc1cc(C)cc(CCC(N)P(O)(=O)CC(Cc2ccccc2)C(O)=O)c1
Structure:
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