Reaction Details Report a problem with these data
Target
Melatonin receptor type 1A
Ligand
BDBM50027444
Substrate
n/a
Meas. Tech.
ChEMBL_1442965 (CHEMBL3378363)
Ki
>10000±n/a nM
Citation
 Párraga, J; Moreno, L; Diaz, A; El Aouad, N; Galán, A; Sanz, MJ; Caignard, DH; Figadčre, B; Cabedo, N; Cortes, D Efficient synthesis of hexahydroindenopyridines and their potential as melatoninergic ligands. Eur J Med Chem 86:700-9 (2014) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1A
Synonyms:
MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A
Type:
Enzyme
Mol. Mass.:
39392.94
Organism:
Homo sapiens (Human)
Description:
P48039
Residue:
350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
  
Inhibitor
Name:
BDBM50027444
Synonyms:
CHEMBL3329384
Type:
Small organic molecule
Emp. Form.:
C19H25NO4
Mol. Mass.:
331.4061
SMILES:
CCOC(=O)CCC(=O)N1CCCC2Cc3ccc(OC)cc3C12
Structure:
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