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Target
ATP-dependent Clp protease proteolytic subunit
Ligand
BDBM50028480
Substrate
n/a
Meas. Tech.
ChEMBL_1437605 (CHEMBL3390207)
Kd
300±n/a nM
Citation
 Goodreid, JD; Wong, K; Leung, E; McCaw, SE; Gray-Owen, SD; Lough, A; Houry, WA; Batey, RA Total synthesis and antibacterial testing of the A54556 cyclic acyldepsipeptides isolated from Streptomyces hawaiiensis. J Nat Prod 77:2170-81 (2014) [PubMed]  Article 
Target
Name:
ATP-dependent Clp protease proteolytic subunit
Synonyms:
ATP-dependent Clp protease proteolytic subunit | CLPP_ECOLI | Caseinolytic protease | Endopeptidase Clp | Heat shock protein F21.5 | JW0427 | Protease Ti | clpP | lopP
Type:
PROTEIN
Mol. Mass.:
23183.39
Organism:
Escherichia coli (strain K12)
Description:
ChEMBL_109492
Residue:
207
Sequence:
MSYSGERDNFAPHMALVPMVIEQTSRGERSFDIYSRLLKERVIFLTGQVEDHMANLIVAQMLFLEAENPEKDIYLYINSPGGVITAGMSIYDTMQFIKPDVSTICMGQAASMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGYQGQATDIEIHAREILKVKGRMNELMALHTGQSLEQIERDTERDRFLSAPEAVEYGLVDSILTHRN
  
Inhibitor
Name:
BDBM50028480
Synonyms:
CHEMBL3342324
Type:
Small organic molecule
Emp. Form.:
C38H50N6O8
Mol. Mass.:
718.839
SMILES:
[H][C@@]12CCCN1C(=O)[C@H](COC(=O)[C@]1([H])C[C@@H](C)CN1C(=O)[C@H](C)NC(=O)[C@H](C)N(C)C2=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)\C=C\C=C\C=C\C |r|
Structure:
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