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Target
Cannabinoid receptor 2
Ligand
BDBM50040984
Substrate
n/a
Meas. Tech.
ChEMBL_1444768 (CHEMBL3378469)
EC50
591±n/a nM
Citation
 Han, S; Thoresen, L; Zhu, X; Narayanan, S; Jung, JK; Strah-Pleynet, S; Decaire, M; Choi, K; Xiong, Y; Yue, D; Semple, G; Thatte, J; Solomon, M; Fu, L; Whelan, K; Al-Shamma, H; Gatlin, J; Chen, R; Dang, H; Pride, C; Gaidarov, I; Unett, DJ; Behan, DP; Sadeque, A; Usmani, KA; Chen, C; Edwards, J; Morgan, M; Jones, RM Discovery of 1a,2,5,5a-tetrahydro-1H-2,3-diaza-cyclopropa[a]pentalen-4-carboxamides as potent and selective CB2 receptor agonists. Bioorg Med Chem Lett 25:322-6 (2014) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CNR2_RAT | Cannabinoid CB2 receptor | Cannabinoid receptor | Cnr2 | rCB2
Type:
Enzyme
Mol. Mass.:
39366.68
Organism:
Rattus norvegicus (Rat)
Description:
Q9QZN9
Residue:
360
Sequence:
MAGCRELELTNGSNGGLEFNPMKEYMILSDAQQIAVAVLCTLMGLLSALENVAVLYLILSSQRLRRKPSYLFIGSLAGADFLASVIFACNFVIFHVFHGVDSRNIFLLKIGSVTMTFTASVGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALGVMWVLSALISYLPLMGWTCCPSPCSELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHQHVASLAEHQDRQVPGIARMRLDVRLAKTLGLVMAVLLICWFPALALMGHSLVTTLSDKVKEAFAFCSMLCLVNSMINPIIYALRSGEIRSAAQHCLTGWKKYLQGLGSEGKEEAPKSSVTETEAEVKTTTGPGSRTPGCSNC
  
Inhibitor
Name:
BDBM50040984
Synonyms:
CHEMBL3354961
Type:
Small organic molecule
Emp. Form.:
C24H27F2N3O
Mol. Mass.:
411.4875
SMILES:
[H][C@]12C[C@@]1([H])c1c(C2)c(nn1-c1ccc(F)cc1F)C(=O)N[C@@H]1[C@]2(C)CC[C@@]([H])(C2)C1(C)C |r|
Structure:
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