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Target
Oxytocin receptor
Ligand
BDBM50044686
Substrate
n/a
Meas. Tech.
ChEMBL_1451726 (CHEMBL3366919)
EC50
0.080000±n/a nM
Citation
 Wisniewski, K; Alagarsamy, S; Galyean, R; Tariga, H; Thompson, D; Ly, B; Wisniewska, H; Qi, S; Croston, G; Laporte, R; Rivière, PJ; Schteingart, CD New, potent, and selective peptidic oxytocin receptor agonists. J Med Chem 57:5306-17 (2014) [PubMed]  Article 
Target
Name:
Oxytocin receptor
Synonyms:
OT-R | OXTR | OXYR_HUMAN | Oxytocin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42793.26
Organism:
Homo sapiens (Human)
Description:
Oxytocin OXTR HEK293::B2R9L7
Residue:
389
Sequence:
MEGALAANWSAEAANASAAPPGAEGNRTAGPPRRNEALARVEVAVLCLILLLALSGNACVLLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLATWLGCLVASAPQVHIFSLREVADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAAAEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWDANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGRRLGETSASKKSNSSSFVLSHRSSSQRSCSQPSTA
  
Inhibitor
Name:
BDBM50044686
Synonyms:
CHEMBL3354594
Type:
Small organic molecule
Emp. Form.:
C48H68FN11O12S
Mol. Mass.:
1042.183
SMILES:
[H][C@]1(NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CCCSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC1=O)C(=O)N(CC(=O)N[C@@H](CC(C)C)C(=O)NCC(N)=O)Cc1ccc(F)cc1)[C@@H](C)CC |r|
Structure:
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