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TargetVasopressin V2 receptor (V2)
LigandBDBM50044777
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1451727
EC50 0.050000±n/a nM
Citation Wisniewski, KAlagarsamy, SGalyean, RTariga, HThompson, DLy, BWisniewska, HQi, SCroston, GLaporte, RRivière, PJSchteingart, CD New, potent, and selective peptidic oxytocin receptor agonists. J Med Chem57:5306-17 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Vasopressin V2 receptor (V2)
Name:Vasopressin receptor
Synonyms:AVPR V2 | AVPR2 | Antidiuretic hormone receptor | Renal-type arginine vasopressin receptor | VASOPRESSIN V2 | Vasopressin V2 receptor
Type:Receptor
Mol. Mass.:40295.28
Organism:Homo sapiens (Human)
Description:P30518
Residue:371
Sequence:
MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLA
ALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQM
VGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQ
RNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLVPGP
SERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEA
PLEGAPFVLLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCARGRTPPSLGPQDESCTT
ASSSLAKDTSS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50044777
NameBDBM50044777
Synonyms:Arginine Vasopressin | Beta-Hypophamine | CHEBI:34543 | Leiormone | Pitressin | VASOPRESSIN | Vasophysin | Vasopressin
TypeSmall organic molecule
Emp. Form.C46H65N15O12S2
Mol. Mass.1084.232
SMILESN[C@H]1CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(N)=O
Structure
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