Reaction Details Report a problem with these data
Target
Vasopressin V2 receptor
Ligand
BDBM50044729
Substrate
n/a
Meas. Tech.
ChEMBL_1451727 (CHEMBL3366920)
EC50
720±n/a nM
Citation
 Wisniewski, K; Alagarsamy, S; Galyean, R; Tariga, H; Thompson, D; Ly, B; Wisniewska, H; Qi, S; Croston, G; Laporte, R; Rivière, PJ; Schteingart, CD New, potent, and selective peptidic oxytocin receptor agonists. J Med Chem 57:5306-17 (2014) [PubMed]  Article 
Target
Name:
Vasopressin V2 receptor
Synonyms:
ADHR | AVPR V2 | AVPR2 | Antidiuretic hormone receptor | DIR | DIR3 | Renal-type arginine vasopressin receptor | V2R | V2R_HUMAN | VASOPRESSIN V2 | Vasopressin V2 receptor | Vasopressin receptor
Type:
Receptor
Mol. Mass.:
40295.28
Organism:
Homo sapiens (Human)
Description:
P30518
Residue:
371
Sequence:
MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEAPLEGAPFVLLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCARGRTPPSLGPQDESCTTASSSLAKDTSS
  
Inhibitor
Name:
BDBM50044729
Synonyms:
CHEMBL3354590
Type:
Small organic molecule
Emp. Form.:
C48H69N11O11S
Mol. Mass.:
1008.194
SMILES:
[H][C@]1(NC(=O)[C@H](Cc2ccccc2)NC(=O)CCSCC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC1=O)C(=O)N(CC(=O)N[C@@H](CC(C)C)C(=O)NCC(N)=O)Cc1ccccc1)[C@@H](C)CC |r|
Structure:
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