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TargetVasopressin V2 receptor (V2)
LigandBDBM50044727
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1451727
EC50 55±n/a nM
Citation Wisniewski, KAlagarsamy, SGalyean, RTariga, HThompson, DLy, BWisniewska, HQi, SCroston, GLaporte, RRivière, PJSchteingart, CD New, potent, and selective peptidic oxytocin receptor agonists. J Med Chem57:5306-17 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Vasopressin V2 receptor (V2)
Name:Vasopressin receptor
Synonyms:AVPR V2 | AVPR2 | Antidiuretic hormone receptor | Renal-type arginine vasopressin receptor | VASOPRESSIN V2 | Vasopressin V2 receptor
Type:Receptor
Mol. Mass.:40295.28
Organism:Homo sapiens (Human)
Description:P30518
Residue:371
Sequence:
MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLA
ALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQM
VGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQ
RNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLVPGP
SERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEA
PLEGAPFVLLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCARGRTPPSLGPQDESCTT
ASSSLAKDTSS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50044727
NameBDBM50044727
Synonyms:CHEMBL3354592
TypeSmall organic molecule
Emp. Form.C49H71N11O12S
Mol. Mass.1038.22
SMILES[H][C@]1(NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CCSCC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC1=O)C(=O)N(CC(=O)N[C@@H](CC(C)C)C(=O)NCC(N)=O)Cc1cccc(C)c1)[C@@H](C)CC |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a