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Target
Serine/threonine-protein kinase 26
Ligand
BDBM50048364
Substrate
n/a
Meas. Tech.
ChEMBL_1446776 (CHEMBL3381091)
IC50
>10000±n/a nM
Citation
 Casale, E; Amboldi, N; Brasca, MG; Caronni, D; Colombo, N; Dalvit, C; Felder, ER; Fogliatto, G; Galvani, A; Isacchi, A; Polucci, P; Riceputi, L; Sola, F; Visco, C; Zuccotto, F; Casuscelli, F Fragment-based hit discovery and structure-based optimization of aminotriazoloquinazolines as novel Hsp90 inhibitors. Bioorg Med Chem 22:4135-50 (2014) [PubMed]  Article 
Target
Name:
Serine/threonine-protein kinase 26
Synonyms:
MASK | MST4 | STK26 | STK26_HUMAN | Serine/threonine-protein kinase MST4
Type:
PROTEIN
Mol. Mass.:
46517.68
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1510631
Residue:
416
Sequence:
MAHSPVAVQVPGMQNNIADPEELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGSALDLLRAGPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTLVGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKFIVKNSKKTSYLTELIDRFKRWKAEGHSDDESDSEGSDSESTSRENNTHPEWSFTTVRKKPDPKKVQNGAEQDLVQTLSCLSMIITPAFAELKQQDENNASRNQAIEELEKSIAVAEAACPGITDKMVKKLIEKFQKCSADESP
  
Inhibitor
Name:
BDBM50048364
Synonyms:
CHEMBL3309997
Type:
Small organic molecule
Emp. Form.:
C19H17N5O3
Mol. Mass.:
363.37
SMILES:
OCCCNc1ccc2c3ncnn3c(nc2c1)-c1ccc2OCOc2c1
Structure:
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