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Target
Lysophosphatidic acid receptor 2
Ligand
BDBM50056350
Substrate
n/a
Meas. Tech.
ChEMBL_1451385 (CHEMBL3363669)
EC50
60±n/a nM
Citation
 Patil, R; Fells, JI; Szabó, E; Lim, KG; Norman, DD; Balogh, A; Patil, S; Strobos, J; Miller, DD; Tigyi, GJ Design and synthesis of sulfamoyl benzoic acid analogues with subnanomolar agonist activity specific to the LPA2 receptor. J Med Chem 57:7136-40 (2014) [PubMed]  Article 
Target
Name:
Lysophosphatidic acid receptor 2
Synonyms:
EDG4 | LPA receptor 2 | LPA-2 | LPA2 | LPAR2 | LPAR2_HUMAN | Lysophosphatidic acid receptor 2 | Lysophosphatidic acid receptor Edg-4
Type:
PROTEIN
Mol. Mass.:
39103.44
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1451385
Residue:
351
Sequence:
MVIMGQCYYNETIGFFYNNSGKELSSHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSVMAVQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLVKTVVIILGAFVVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRTFRRLLCCACLRQSTRESVHYTSSAQGGASTRIMLPENGHPLMDSTL
  
Inhibitor
Name:
BDBM50056350
Synonyms:
CHEMBL3322508
Type:
Small organic molecule
Emp. Form.:
C23H19BrN2O6S
Mol. Mass.:
531.376
SMILES:
OC(=O)c1cc(Br)ccc1S(=O)(=O)NCCCCN1C(=O)c2cccc3cccc(C1=O)c23
Structure:
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