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Target
Ceramide transfer protein
Ligand
BDBM50067351
Substrate
n/a
Meas. Tech.
ChEMBL_1465154 (CHEMBL3405855)
EC50
159000±n/a nM
Citation
 Santos, C; Fleury, L; Rodriguez, F; Markus, J; Berke?, D; Daïch, A; Ausseil, F; Baudoin-Dehoux, C; Ballereau, S; Génisson, Y The CERT antagonist HPA-12: first practical synthesis and individual binding evaluation of the four stereoisomers. Bioorg Med Chem 23:2004-9 (2015) [PubMed]  Article 
Target
Name:
Ceramide transfer protein
Synonyms:
CERT | CERT | CERT1 | CERT_HUMAN | COL4A3BP | Ceramide transfer protein | Collagen type IV alpha-3-binding protein | GPBP | Goodpasture antigen-binding protein | STARD11 | START domain-containing protein 11 | StAR-related lipid transfer protein 11 | hCERT
Type:
PROTEIN
Mol. Mass.:
70818.45
Organism:
Homo sapiens (Human)
Description:
ChEMBL_109569
Residue:
624
Sequence:
MSDNQSWNSSGSEEDPETESGPPVERCGVLSKWTNYIHGWQDRWVVLKNNALSYYKSEDETEYGCRGSICLSKAVITPHDFDECRFDISVNDSVWYLRAQDPDHRQQWIDAIEQHKTESGYGSESSLRRHGSMVSLVSGASGYSATSTSSFKKGHSLREKLAEMETFRDILCRQVDTLQKYFDACADAVSKDELQRDKVVEDDEDDFPTTRSDGDFLHSTNGNKEKLFPHVTPKGINGIDFKGEAITFKATTAGILATLSHCIELMVKREDSWQKRLDKETEKKRRTEEAYKNAMTELKKKSHFGGPDYEEGPNSLINEEEFFDAVEAALDRQDKIEEQSQSEKVRLHWPTSLPSGDAFSSVGTHRFVQKPYSRSSSMSSIDLVSASDDVHRFSSQVEEMVQNHMTYSLQDVGGDANWQLVVEEGEMKVYRREVEENGIVLDPLKATHAVKGVTGHEVCNYFWNVDVRNDWETTIENFHVVETLADNAIIIYQTHKRVWPASQRDVLYLSVIRKIPALTENDPETWIVCNFSVDHDSAPLNNRCVRAKINVAMICQTLVSPPEGNQEISRDNILCKITYVANVNPGGWAPASVLRAVAKREYPKFLKRFTSYVQEKTAGKPILF
  
Inhibitor
Name:
BDBM50067351
Synonyms:
CHEMBL3401791
Type:
Small organic molecule
Emp. Form.:
C22H37NO3
Mol. Mass.:
363.5341
SMILES:
CCCCCCCCCCCC(=O)N[C@H](CO)C[C@@H](O)c1ccccc1 |r|
Structure:
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