Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM50078765
Substrate
n/a
Meas. Tech.
ChEMBL_1472331 (CHEMBL3419681)
EC50
12±n/a nM
Citation
 Ogawa, G; Tius, MA; Zhou, H; Nikas, SP; Halikhedkar, A; Mallipeddi, S; Makriyannis, A 3'-functionalized adamantyl cannabinoid receptor probes. J Med Chem 58:3104-16 (2015) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_RAT | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cnr1 | Skr6
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52856.55
Organism:
Rattus norvegicus (rat)
Description:
P20272
Residue:
473
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEENIQCGENFMDMECFMILNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHVFHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50078765
Synonyms:
CHEMBL3416124
Type:
Small organic molecule
Emp. Form.:
C26H33NO3S
Mol. Mass.:
439.61
SMILES:
[H][C@@]12C[C@H](O)CC[C@@]1([H])C(C)(C)Oc1cc(cc(O)c21)[C@@]12CC3CC(C[C@](C3)(C1)N=C=S)C2 |r,TLB:23:24:21.22.27:28,27:22:32:26.28.25,27:26:32:21.22.23,29:26:32:21.22.23|
Structure:
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