Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 23
Ligand
BDBM50087856
Substrate
n/a
Meas. Tech.
ChEMBL_1476070 (CHEMBL3428700)
pH
7±n/a
IC50
11400±n/a nM
Comments
extracted
Citation
 He, Y; Guo, X; Yu, ZH; Wu, L; Gunawan, AM; Zhang, Y; Dixon, JE; Zhang, ZY A potent and selective inhibitor for the UBLCP1 proteasome phosphatase. Bioorg Med Chem 23:2798-809 (2015) [PubMed]  Article 
Target
Name:
Dual specificity protein phosphatase 23
Synonyms:
DUS23_HUMAN | DUSP23 | Dual specificity protein phosphatase 23 | Dual specificity protein phosphatase 23 (VHZ) | LDP-3 | LDP3 | Low molecular mass dual specificity phosphatase 3 | VH1-like phosphatase Z | VHZ
Type:
Enzyme
Mol. Mass.:
16592.49
Organism:
Homo sapiens (Human)
Description:
Q9BVJ7
Residue:
150
Sequence:
MGVQPPNFSWVLPGRLAGLALPRLPAHYQFLLDLGVRHLVSLTERGPPHSDSCPGLTLHRLRIPDFCPPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQFYQRTK
  
Inhibitor
Name:
BDBM50087856
Synonyms:
CHEMBL3426913
Type:
Small organic molecule
Emp. Form.:
C28H30F3NO6
Mol. Mass.:
533.5361
SMILES:
CCCCC(Oc1cc(O)c(cc1C#Cc1ccccc1OC(F)(F)F)C(O)=O)C(=O)NC1CCCCC1
Structure:
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