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TargetArylacetamide deacetylase
LigandBDBM50370232
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1481147
Ki 200000±n/a nM
Citation Kobayashi, YFukami, TNakajima, AWatanabe, ANakajima, MYokoi, T Species differences in tissue distribution and enzyme activities of arylacetamide deacetylase in human, rat, and mouse. Drug Metab Dispos40:671-9 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Arylacetamide deacetylase
Name:Arylacetamide deacetylase
Synonyms:AADAC | Arylacetamide deacetylase | DAC
Type:PROTEIN
Mol. Mass.:45743.18
Organism:Homo sapiens
Description:ChEMBL_109673
Residue:399
Sequence:
MGRKSLYLLIVGILIAYYIYTPLPDNVEEPWRMMWINAHLKTIQNLATFVELLGLHHFMD
SFKVVGSFDEVPPTSDENVTVTETKFNNILVRVYVPKRKSEALRRGLFYIHGGGWCVGSA
ALSGYDLLSRWTADRLDAVVVSTNYRLAPKYHFPIQFEDVYNALRWFLRKKVLAKYGVNP
ERIGISGDSAGGNLAAAVTQQLLDDPDVKIKLKIQSLIYPALQPLDVDLPSYQENSNFLF
LSKSLMVRFWSEYFTTDRSLEKAMLSRQHVPVESSHLFKFVNWSSLLPERFIKGHVYNNP
NYGSSELAKKYPGFLDVRAAPLLADDNKLRGLPLTYVITCQYDLLRDDGLMYVTRLRNTG
VQVTHNHVEDGFHGAFSFLGLKISHRLINQYIEWLKENL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50370232
NameBDBM50370232
Synonyms:BA-41166E | L-5103 | RIFAMPIN | Rifadin | Rifampicin
TypeSmall organic molecule
Emp. Form.C43H58N4O12
Mol. Mass.822.9402
SMILESCO[C@H]1\C=C\O[C@@]2(C)Oc3c(C2=O)c2c(O)c(\C=N\N4CCN(C)CC4)c(NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)c(O)c2c(O)c3C |r,c:33,t:3,35|
Structure
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