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Target
Arylacetamide deacetylase
Ligand
BDBM50370232
Substrate
n/a
Meas. Tech.
ChEMBL_1481146 (CHEMBL3537676)
Ki
300000±n/a nM
Citation
 Kobayashi, Y; Fukami, T; Nakajima, A; Watanabe, A; Nakajima, M; Yokoi, T Species differences in tissue distribution and enzyme activities of arylacetamide deacetylase in human, rat, and mouse. Drug Metab Dispos 40:671-9 (2012) [PubMed]  Article 
Target
Name:
Arylacetamide deacetylase
Synonyms:
AAAD_HUMAN | AADAC | Arylacetamide deacetylase | DAC
Type:
PROTEIN
Mol. Mass.:
45743.18
Organism:
Homo sapiens (Human)
Description:
ChEMBL_109673
Residue:
399
Sequence:
MGRKSLYLLIVGILIAYYIYTPLPDNVEEPWRMMWINAHLKTIQNLATFVELLGLHHFMDSFKVVGSFDEVPPTSDENVTVTETKFNNILVRVYVPKRKSEALRRGLFYIHGGGWCVGSAALSGYDLLSRWTADRLDAVVVSTNYRLAPKYHFPIQFEDVYNALRWFLRKKVLAKYGVNPERIGISGDSAGGNLAAAVTQQLLDDPDVKIKLKIQSLIYPALQPLDVDLPSYQENSNFLFLSKSLMVRFWSEYFTTDRSLEKAMLSRQHVPVESSHLFKFVNWSSLLPERFIKGHVYNNPNYGSSELAKKYPGFLDVRAAPLLADDNKLRGLPLTYVITCQYDLLRDDGLMYVTRLRNTGVQVTHNHVEDGFHGAFSFLGLKISHRLINQYIEWLKENL
  
Inhibitor
Name:
BDBM50370232
Synonyms:
BA-41166E | L-5103 | RIFAMPIN | Rifadin | Rifampicin
Type:
Small organic molecule
Emp. Form.:
C43H58N4O12
Mol. Mass.:
822.9402
SMILES:
CO[C@H]1\C=C\O[C@@]2(C)Oc3c(C2=O)c2c(O)c(\C=N\N4CCN(C)CC4)c(NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)c(O)c2c(O)c3C |r,c:33,t:3,35|
Structure:
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