Reaction Details Report a problem with these data
Target
Carbonic anhydrase
Ligand
BDBM50098589
Substrate
n/a
Meas. Tech.
ChEMBL_1507030 (CHEMBL3599984)
pH
8.3±n/a
Ki
9100000±n/a nM
Comments
extracted
Citation
 Pinard, MA; Lotlikar, SR; Boone, CD; Vullo, D; Supuran, CT; Patrauchan, MA; McKenna, R Structure and inhibition studies of a type II beta-carbonic anhydrase psCA3 from Pseudomonas aeruginosa. Bioorg Med Chem 23:4831-8 (2015) [PubMed]  Article 
Target
Name:
Carbonic anhydrase
Synonyms:
Carbonate dehydratase | Carbonic anhydrase
Type:
PROTEIN
Mol. Mass.:
24220.80
Organism:
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228)
Description:
ChEMBL_109845
Residue:
215
Sequence:
MSDLQQLFENNVRWAEAIKQEDPDFFAKLARQQTPEYLWIGCSDARVPANEIVGMLPGDLFVHRNVANVVLHTDLNCLSVIQFAVDVLKVKHILVTGHYGCGGVRASLHNDQLGLIDGWLRSIRDLAYEYREHLEQLPTEEERVDRLCELNVIQQVANVSHTSIVQNAWHRGQSLSVHGCIYGIKDGLWKNLNVTVSGLDQLPPQYRLSPLGGCC
  
Inhibitor
Name:
BDBM50098589
Synonyms:
E285 | Sodium tetraborate
Type:
Small organic molecule
Emp. Form.:
B4Na2O7
Mol. Mass.:
201.219
SMILES:
[Na+].[Na+].[O-]B(OB=O)OB([O-])OB=O
Structure:
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