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TargetC-C chemokine receptor type 9
LigandBDBM50398334
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1510357
IC50 11±n/a nM
Citation Zhang, JRomero, JChan, AGoss, JStucka, SCross, JChamberlain, BVaroglu, MChandonnet, HRyan, DLippa, B Biarylsulfonamide CCR9 inhibitors for inflammatory bowel disease. Bioorg Med Chem Lett25:3661-4 (2015) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
C-C chemokine receptor type 9
Name:C-C chemokine receptor type 9
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:42023.90
Organism:Homo sapiens (Human)
Description:ChEMBL_1510356
Residue:369
Sequence:
MTPTDFTSPIPNMADDYGSESTSSMEDYVNFNFTDFYCEKNNVRQFASHFLPPLYWLVFI
VGALGNSLVILVYWYCTRVKTMTDMFLLNLAIADLLFLVTLPFWAIAAADQWKFQTFMCK
VVNSMYKMNFYSCVLLIMCISVDRYIAIAQAMRAHTWREKRLLYSKMVCFTIWVLAAALC
IPEILYSQIKEESGIAICTMVYPSDESTKLKSAVLTLKVILGFFLPFVVMACCYTIIIHT
LIQAKKSSKHKALKVTITVLTVFVLSQFPYNCILLVQTIDAYAMFISNCAVSTNIDICFQ
VTQTIAFFHSCLNPVLYVFVGERFRRDLVKTLKNLGCISQAQWVSFTRREGSLKLSSMLL
ETTSGALSL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50398334
NameBDBM50398334
Synonyms:CHEMBL2178578
TypeSmall organic molecule
Emp. Form.C22H21ClN2O4S
Mol. Mass.444.931
SMILESCC(C)(C)c1ccc(cc1)S(=O)(=O)Nc1ccc(Cl)cc1C(=O)c1cc[n+]([O-])cc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a