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Target
Mu-type opioid receptor
Ligand
BDBM50119519
Substrate
n/a
Meas. Tech.
ChEMBL_1515755 (CHEMBL3614308)
IC50
1020±n/a nM
Citation
 Deekonda, S; Wugalter, L; Kulkarni, V; Rankin, D; Largent-Milnes, TM; Davis, P; Bassirirad, NM; Lai, J; Vanderah, TW; Porreca, F; Hruby, VJ Discovery of 5-substituted tetrahydronaphthalen-2yl-methyl with N-phenyl-N-(piperidin-4-yl)propionamide derivatives as potent opioid receptor ligands. Bioorg Med Chem 23:6185-94 (2015) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50119519
Synonyms:
CHEMBL3613884
Type:
Small organic molecule
Emp. Form.:
C27H34F3N3O3
Mol. Mass.:
505.5724
SMILES:
OC(=O)C(F)(F)F.CCC(=O)N(C1CCN(Cc2ccc3[C@H](N)CCCc3c2)CC1)c1ccccc1 |r|
Structure:
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