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Target
Acetylcholine-binding protein
Ligand
BDBM50120209
Substrate
n/a
Meas. Tech.
ChEMBL_1518279 (CHEMBL3620254)
Kd
160±n/a nM
Citation
 Bach, TB; Jensen, AA; Petersen, JG; Sørensen, TE; Della Volpe, S; Liu, J; Blaazer, AR; van Muijlwijk-Koezen, JE; Balle, T; Frølund, B Exploration of the molecular architecture of the orthosteric binding site in thea4ß2 nicotinic acetylcholine receptor with analogs of 3-(dimethylamino)butyl dimethylcarbamate (DMABC) and 1-(pyridin-3-yl)-1,4-diazepane. Eur J Med Chem 102:425-44 (2015) [PubMed]  Article 
Target
Name:
Acetylcholine-binding protein
Synonyms:
ACHP_LYMST | ACh-binding protein | Acetylcholine Binding protein | Acetylcholine-binding protein (AchBP) | Acetylcholine-binding protein (Ls-AchBP) | AchBP
Type:
n/a
Mol. Mass.:
26055.52
Organism:
Lymnaea stagnalis
Description:
Soluble acetylcholine receptor
Residue:
229
Sequence:
MRRNIFCLACLWIVQACLSLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRSEIL
  
Inhibitor
Name:
BDBM50120209
Synonyms:
CHEMBL3616575
Type:
Small organic molecule
Emp. Form.:
C17H21N3
Mol. Mass.:
267.3687
SMILES:
C(N1CCCN(CC1)c1cccnc1)c1ccccc1
Structure:
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