Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM110163
Substrate
n/a
Meas. Tech.
ChEMBL_1518649 (CHEMBL3619715)
Ki
209±n/a nM
Citation
 Van der Walt, MM; Terre'Blanche, G 1,3,7-Triethyl-substituted xanthines--possess nanomolar affinity for the adenosine A1 receptor. Bioorg Med Chem 23:6641-9 (2015) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM110163
Synonyms:
8-(3-Phenylpropyl)-1,3,7-triethylxanthine (9d)
Type:
Small organic molecule
Emp. Form.:
C20H26N4O2
Mol. Mass.:
354.446
SMILES:
CCn1c(CCCc2ccccc2)nc2n(CC)c(=O)n(CC)c(=O)c12
Structure:
Search PDB for entries with ligand similarity: