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Target
Mu-type opioid receptor
Ligand
BDBM50123600
Substrate
n/a
Meas. Tech.
ChEMBL_1521811 (CHEMBL3626671)
Ki
>1000±n/a nM
Citation
 Lee, DY; Deng, G; Ma, Z; Xu, W; Yang, L; Liu, J; Dai, R; Liu-Chen, LY Synthesis and biological evaluation of 2-alkyl-2-methoxymethyl-salvinorin ethers as selectiveż-opioid receptor agonists. Bioorg Med Chem Lett 25:4689-92 (2015) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
MOR-1 | MUOR1 | Mu-type opioid receptor (MOR) | OPIATE Mu | OPRM_RAT | Opiate non-selective | Opioid receptor B | Oprm1 | Ror-b
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44503.11
Organism:
Rattus norvegicus (rat)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the mu opioid receptor.
Residue:
398
Sequence:
MDSSTGPGNTSDCSDPLAQASCSPAPGSWLNLSHVDGNQSDPCGLNRTGLGGNDSLCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSTRVRQNTREHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50123600
Synonyms:
CHEMBL3622718
Type:
Small organic molecule
Emp. Form.:
C27H37IO8
Mol. Mass.:
616.4824
SMILES:
[H][C@]12CC[C@@]3(C)[C@@H](C[C@](CCOCCI)(COC)C(=O)[C@]3([H])[C@@]1(C)C[C@H](OC2=O)c1ccoc1)C(=O)OC |r|
Structure:
Search PDB for entries with ligand similarity: