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TargetAcidic alpha-glucosidase
LigandBDBM50123929
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1519500
Ki 1960000±n/a nM
Citation Ramadhan, RPhuwapraisirisan, P New arylalkanones from Horsfieldia macrobotrys, effective antidiabetic agents concomitantly inhibitinga-glucosidase and free radicals. Bioorg Med Chem Lett25:4529-33 (2015) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Acidic alpha-glucosidase
Name:Acidic alpha-glucosidase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:106191.24
Organism:Rattus norvegicus
Description:ChEMBL_1506157
Residue:953
Sequence:
MNIRKPLCSNSVVGACTLVSLTTAVILGHLMLRELMLLPQDLHESSSGLWKTYRPHHQES
YEPAPLHIQEHAEQLRAVPTQCDVTPNSRFDCAPDKGITQEQCEARGCCWVPAGQVLNGP
VMGQPWCFFPPSYPSYRLENLSSTESGYTATLTRTSPTFFPKDVLTLQLEVLMETDSRLH
FMIKDPTSKRYEVPLETPRVLSQAPSPLYSVEFSEEPFGVIVRRKLGGRVLLNTTVAPLF
FADQFLQLSTSLPSQHIAGLGEHLSPLMLSTEWTRITLWNRDVAPSQGVNLYGSHPFYLA
LEDGGLAHGVFLLNSNAMDVVLQPSPALTWRSTGGILDVYVFLGPEPKSVVQQYLDVVGY
PFMPPYWGLGFHLCRWGYSSTAIVRQVVENMTRTHFPLDVQWNDLDYMDARRDFTFNQDG
FADFPDMVHELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLIGKV
WPGSTAFPDFTNPETLDWWQDMVSEFHAQVPFDGMWIDMNEPSNFIRGSQQGCPDNELEN
PPYVPGVVGGALQAATICASSHQFLSTHYNLHNLYGLTEAIASSRALVKTRGTRPFVISR
STFAGHGRYAGHWTGDVWSSWEHLAYSVPEILQFNLLGVPLVGADICGFQGNTTEELCVR
WTQLGAFYPFMRNHNDLNSLPQEPYRFSETAQQAMRKAFTLRYALLPYLYTLFHGAHVKG
DTVARPLFLEFPEDPSTWSVDRQLLWGPALLITPVLEPGKTDVTGYFPKGMWYNLQMVPV
ETLGSLPSSSPASSFRSIVHSKGQWLTLEAPLDTINVHLRAGYIIPLQGPSLTTTESRKQ
PMALAVALTESGEASGELFWDDGESLGVLERGAYTLVTFSAKNNTIVNKLVHVTKEGGEL
QLREVTILGVTTAPTQVLSNGISVSNFTYSPDDKSLSIPVSLLMGERFQIDWS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50123929
n/a
NameBDBM50123929
Synonyms:CHEMBL3621760
TypeSmall organic molecule
Emp. Form.C36H40O7
Mol. Mass.584.6986
SMILESO[C@@H](CCCCCCCC(=O)c1c(O)cc(O)c(C(CCc2ccccc2)c2ccc(O)cc2O)c1O)c1ccccc1 |r|
Structure
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